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A recent study in Retina (July / August 2009 - vol 29 - 932-940 ps) seems to indicate the improvement in outcome in patients with retinal vein occlusion treated with low doses of fibrinolytics compared to those treated with hemodilution.
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The RESEARCHERS s ( Hattenbach, Lars-Olof MD; FRIEDRICH ARNDT, CARL MD; Lerche, RALF MD; Scharrer, INGE MD; Baatz, Holger MD, margin, FABRICE MD; Richard, Gisbert MD; BEHRENS- BAUMANN, WOLFGANG MD; OHRLOFF, CHRISTIAN MD ) Ometer s randomly 53 patients with occlusion of the central retinal vein (CRVO) or occlusion of branch retinal vein (BRVO ) to treatment with intravenous thrombolysis with 50 mg of recombinant tissue plasminogen activator (rt-PA) or hemodilution within the 11 days of onset of symptoms.
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All patients were followed up one year.
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Among patients with CRVO half BCVA was 20/60 in the rt-PA group compared to a BCVA of 20/400 in the hemodilution group.
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Among patients with BRVO, there was a trend toward improved vision in rt-PA group differences did not reach statistical significance, probably due to the small number of patients group.
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Basic information and guidance. For personalized information consult your ophthalmologist.
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CEUTA EYES. INNOVATION IN OPHTHALMOLOGY. x
The RESEARCHERS s ( Hattenbach, Lars-Olof MD; FRIEDRICH ARNDT, CARL MD; Lerche, RALF MD; Scharrer, INGE MD; Baatz, Holger MD, margin, FABRICE MD; Richard, Gisbert MD; BEHRENS- BAUMANN, WOLFGANG MD; OHRLOFF, CHRISTIAN MD ) Ometer s randomly 53 patients with occlusion of the central retinal vein (CRVO) or occlusion of branch retinal vein (BRVO ) to treatment with intravenous thrombolysis with 50 mg of recombinant tissue plasminogen activator (rt-PA) or hemodilution within the 11 days of onset of symptoms.
x
All patients were followed up one year.
x
Among patients with CRVO half BCVA was 20/60 in the rt-PA group compared to a BCVA of 20/400 in the hemodilution group.
x
Among patients with BRVO, there was a trend toward improved vision in rt-PA group differences did not reach statistical significance, probably due to the small number of patients group.
x
Basic information and guidance. For personalized information consult your ophthalmologist.
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EYE CENTER DR. CATOIRA MEDIN
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